Either -

Take Cerrillos Road south to the intersection of Airport Road and Cerrillos Road, across from the Santa Fe Place Mall. Turn right (west) onto Airport Road and continue for three miles to the NM Hwy 599 traffic signal. Continue through the traffic signal for about 100 yards. You will see a sign pointing the way to the airport. Turn left and follow Aviation Drive to the airport terminal.

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Take St Francis Drive (Hwy 285/84) north toward Los Alamos and Espanola.  Take the Hwy 599 Exit just north of Santa Fe.  Follow Hwy 599 southbound.  Turn right at Airport Road (traffic signal) and go about 100 yards.  You will see a sign pointing the way to the airport.  Turn left and follow Aviation Drive to the airport terminal.

Follow Hwy 599 southbound. Turn right at Airport Road (traffic signal) and go about 100 yards. You will see a sign pointing the way to the airport. Turn left and follow Aviation Drive to the airport terminal.

Take I-25 to the NM Hwy 599 exit (Exit 276). Take Hwy 599 to the west toward Los Alamos and Espanola. Follow 599 for about three miles until you reach the traffic signal at Airport Road. Turn left and go about 100 yards. You will see a sign pointing the way to the airport. Turn left and follow Aviation Drive to the airport terminal.